Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection cycle. We have performed a genome-wide siRNA sc...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Deffrasnes, Celine, Marsh, Glenn A., Foo, Chwan Hong, Rootes, Christina L., Gould, Cathryn M., Grusovin, Julian, Monaghan, Paul, Lo, Michael K., Tompkins, S. Mark, Adams, Timothy E., Lowenthal, John W., Simpson, Kaylene J., Stewart, Cameron R., Bean, Andrew G. D., Wang, Lin-Fa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806981/
https://ncbi.nlm.nih.gov/pubmed/27010548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005478
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