Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection cycle. We have performed a genome-wide siRNA sc...

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Publicat a:PLoS Pathog
Autors principals: Deffrasnes, Celine, Marsh, Glenn A., Foo, Chwan Hong, Rootes, Christina L., Gould, Cathryn M., Grusovin, Julian, Monaghan, Paul, Lo, Michael K., Tompkins, S. Mark, Adams, Timothy E., Lowenthal, John W., Simpson, Kaylene J., Stewart, Cameron R., Bean, Andrew G. D., Wang, Lin-Fa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806981/
https://ncbi.nlm.nih.gov/pubmed/27010548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005478
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