Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection cycle. We have performed a genome-wide siRNA sc...

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Publicado en:PLoS Pathog
Autores principales: Deffrasnes, Celine, Marsh, Glenn A., Foo, Chwan Hong, Rootes, Christina L., Gould, Cathryn M., Grusovin, Julian, Monaghan, Paul, Lo, Michael K., Tompkins, S. Mark, Adams, Timothy E., Lowenthal, John W., Simpson, Kaylene J., Stewart, Cameron R., Bean, Andrew G. D., Wang, Lin-Fa
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806981/
https://ncbi.nlm.nih.gov/pubmed/27010548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005478
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