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A Bayesian Assignment Method for Ambiguous Bisulfite Short Reads
DNA methylation is an epigenetic modification critical for normal development and diseases. The determination of genome-wide DNA methylation at single-nucleotide resolution is made possible by sequencing bisulfite treated DNA with next generation high-throughput sequencing. However, aligning bisulfi...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806927/ https://ncbi.nlm.nih.gov/pubmed/27011215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151826 |
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