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Large-scale analysis of 48 DNA and 48 RNA tetranucleotides studied by 1 μs explicit-solvent molecular dynamics simulations

An understanding of how the conformational behavior of single-stranded DNAs and RNAs depend on sequence is likely to be important for attempts to rationalize the thermodynamics of nucleic acid folding. In an attempt to further our understanding of such sequence dependences we report here the results...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Schrodt, Michael V., Andrews, Casey T., Elcock, Adrian H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806854/
https://ncbi.nlm.nih.gov/pubmed/26580891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.5b00899
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