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A high-throughput in vivo micronucleus assay for genome instability screening in mice
We describe a sensitive, robust, high-throughput method for quantifying the formation of micronuclei, markers of genome instability, in mouse erythrocytes. Micronuclei are whole chromosomes or chromosome segments that have been separated from the nucleus. Other methods of detection rely on labour-in...
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| Publicado no: | Nat Protoc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806852/ https://ncbi.nlm.nih.gov/pubmed/25551665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.010 |
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