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Apparent Activity in High-Throughput Screening: Origins of Compound-Dependent Assay Interference
Expansive compound collections made up of structurally heterogeneous chemicals, the activities of which are largely undefined, present challenging problems for high-throughput screening (HTS). Foremost is differentiating whether the activity for a given compound in an assay is directed against the t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878863/ https://ncbi.nlm.nih.gov/pubmed/20417149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.03.020 |
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