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Complex molecular and functional outcomes of single versus sequential cytokine stimulation of rat microglia

BACKGROUND: Microglia are the “professional” phagocytes of the CNS. Phagocytosis is crucial for normal CNS development and maintenance, but it can be either beneficial or detrimental after injury or disease. For instance, white matter damage releases myelin debris that must be cleared by microglia i...

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Pubblicato in:J Neuroinflammation
Autori principali: Siddiqui, Tamjeed A., Lively, Starlee, Schlichter, Lyanne C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806433/
https://ncbi.nlm.nih.gov/pubmed/27009332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0531-9
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