Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts

Cardiac progenitor cells are multipotent and give rise to cardiac endothelium, smooth muscle, and cardiomyocytes. Here, we define and characterize the cardiomyoblast intermediate that is committed to the cardiomyocyte fate, and we characterize the niche signals that regulate commitment. Cardiomyobla...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Jain, Rajan, Li, Deqiang, Gupta, Mudit, Manderfield, Lauren J., Ifkovits, Jamie L., Wang, Qiaohong, Liu, Feiyan, Liu, Ying, Poleshko, Andrey, Padmanabhan, Arun, Raum, Jeffrey C., Li, Li, Morrisey, Edward E., Lu, Min Min, Won, Kyoung-Jae, Epstein, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806339/
https://ncbi.nlm.nih.gov/pubmed/26113728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa6071
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