Plasticity of Hopx(+) Type I alveolar cells to regenerate Type II cells in the lung

The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense research. Pulmonary alveolar Type II cells produce surfactant and function as progenitors in the adult, demonstrating both self-renewal and differentiation into gas exchanging Type I cells. In vivo, Type...

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Publicado no:Nat Commun
Main Authors: Jain, Rajan, Barkauskas, Christina E., Takeda, Norifumi, Bowie, Emily J., Aghajanian, Haig, Wang, Qiaohong, Padmanabhan, Arun, Manderfield, Lauren J., Gupta, Mudit, Li, Deqiang, Li, Li, Trivedi, Chinmay M., Hogan, Brigid L. M., Epstein, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396689/
https://ncbi.nlm.nih.gov/pubmed/25865356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7727
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