Llwytho...

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses

Reston viruses are the only Ebolaviruses that are not pathogenic in humans. We analyzed 196 Ebolavirus genomes and identified specificity determining positions (SDPs) in all nine Ebolavirus proteins that distinguish Reston viruses from the four human pathogenic Ebolaviruses. A subset of these SDPs w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Pappalardo, Morena, Juliá, Miguel, Howard, Mark J., Rossman, Jeremy S., Michaelis, Martin, Wass, Mark N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806318/
https://ncbi.nlm.nih.gov/pubmed/27009368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23743
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!