Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

Cockayne syndrome (CS) is a severe neurodevelopmental disorder characterized by growth abnormalities, premature aging, and photosensitivity. Mutation of Cockayne syndrome B (CSB) affects neuronal gene expression and differentiation, so we attempted to bypass its function by expressing downstream tar...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wang, Yuming, Jones-Tabah, Jace, Chakravarty, Probir, Stewart, Aengus, Muotri, Alysson, Laposa, Rebecca R., Svejstrup, Jesper Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806223/
https://ncbi.nlm.nih.gov/pubmed/26972010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.051
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