Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

The HIV-1 envelope glycoprotein trimer is covered by an array of N-linked glycans that shield it from immune surveillance. The high density of glycans on the trimer surface imposes steric constraints limiting the actions of glycan-processing enzymes, so that multiple under-processed structures remai...

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發表在:Cell Rep
Main Authors: Behrens, Anna-Janina, Vasiljevic, Snezana, Pritchard, Laura K., Harvey, David J., Andev, Rajinder S., Krumm, Stefanie A., Struwe, Weston B., Cupo, Albert, Kumar, Abhinav, Zitzmann, Nicole, Seabright, Gemma E., Kramer, Holger B., Spencer, Daniel I.R., Royle, Louise, Lee, Jeong Hyun, Klasse, Per J., Burton, Dennis R., Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Moore, John P., Doores, Katie J., Crispin, Max
格式: Artigo
語言:Inglês
出版: Cell Press 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805854/
https://ncbi.nlm.nih.gov/pubmed/26972002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.058
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