A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure

The interplay between bacterial antimicrobial susceptibility, phylogenetics and patient outcome is poorly understood. During a typhoid clinical treatment trial in Nepal, we observed several treatment failures and isolated highly fluoroquinolone-resistant Salmonella Typhi (S. Typhi). Seventy-eight S....

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Pham Thanh, Duy, Karkey, Abhilasha, Dongol, Sabina, Ho Thi, Nhan, Thompson, Corinne N, Rabaa, Maia A, Arjyal, Amit, Holt, Kathryn E, Wong, Vanessa, Tran Vu Thieu, Nga, Voong Vinh, Phat, Ha Thanh, Tuyen, Pradhan, Ashish, Shrestha, Saroj Kumar, Gajurel, Damoder, Pickard, Derek, Parry, Christopher M, Dougan, Gordon, Wolbers, Marcel, Dolecek, Christiane, Thwaites, Guy E, Basnyat, Buddha, Baker, Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2016
Gaiak:
Epidemiology and Global Health
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805543/
https://ncbi.nlm.nih.gov/pubmed/26974227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14003
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