Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells.

Nck, an oncogenic protein composed of one SH2 and three SH3 domains, is a common target for various cell surface receptors. Nck is thought to function as an adaptor protein to couple cell surface receptors to downstream effector molecules that regulate cellular responses induced by receptor activati...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lee, C H, Li, W, Nishimura, R, Zhou, M, Batzer, A G, Myers, M G, White, M F, Schlessinger, J, Skolnik, E Y
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11713
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