Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells.

Eitemau Tebyg

• The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.
  gan: Skolnik, E Y, et al.
  Cyhoeddwyd: (1993)
• The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.
  gan: Li, W, et al.
  Cyhoeddwyd: (1992)
• Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase.
  gan: Chuang, L M, et al.
  Cyhoeddwyd: (1993)
• Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation.
  gan: Backer, J M, et al.
  Cyhoeddwyd: (1992)
• Role of IRS-1-GRB-2 complexes in insulin signaling.
  gan: Myers, M G, et al.
  Cyhoeddwyd: (1994)