Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells.

Nck, an oncogenic protein composed of one SH2 and three SH3 domains, is a common target for various cell surface receptors. Nck is thought to function as an adaptor protein to couple cell surface receptors to downstream effector molecules that regulate cellular responses induced by receptor activati...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Lee, C H, Li, W, Nishimura, R, Zhou, M, Batzer, A G, Myers, M G, White, M F, Schlessinger, J, Skolnik, E Y
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11713
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