Chronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung Cancer

Mutations in epithelial growth factor receptor (EGFR), as well as in the EGFR downstream target KRAS are frequently observed in non-small cell lung cancer (NSCLC). Chronic obstructive pulmonary disease (COPD), an independent risk factor for developing NSCLC, is associated with an increased activatio...

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Veröffentlicht in:PLoS One
Hauptverfasser: Saber, Ali, van der Wekken, Anthonie J., Kerner, Gerald S. M. A., van den Berge, Maarten, Timens, Wim, Schuuring, Ed, ter Elst, Arja, van den Berg, Anke, Hiltermann, T. Jeroen N., Groen, Harry J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805285/
https://ncbi.nlm.nih.gov/pubmed/27008036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152317
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