Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

Extracellular α-synuclein has been proposed as a crucial mechanism for induction of pathological aggregate formation in previously healthy cells. In vitro, extracellular α-synuclein is partially associated with exosomal vesicles. Recently, we have provided evidence that exosomal α-synuclein is prese...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain
Hauptverfasser: Stuendl, Anne, Kunadt, Marcel, Kruse, Niels, Bartels, Claudia, Moebius, Wiebke, Danzer, Karin M., Mollenhauer, Brit, Schneider, Anja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805087/
https://ncbi.nlm.nih.gov/pubmed/26647156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv346
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