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Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex

The reassortment of influenza viral gene segments plays a key role in the genesis of pandemic strains. All of the last three pandemic viruses contained reassorted polymerase complexes with subunits derived from animal viruses, suggesting that the acquisition of a reassorted polymerase complex might...

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Detalles Bibliográficos
Publicado en:J Gen Virol
Main Authors: Chin, Alex W. H., Yen, Hui-L., Krauss, Scott, Webby, Richard J., Poon, Leo L. M.
Formato: Artigo
Idioma:Inglês
Publicado: Microbiology Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804605/
https://ncbi.nlm.nih.gov/pubmed/26703222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000385
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