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Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex

The reassortment of influenza viral gene segments plays a key role in the genesis of pandemic strains. All of the last three pandemic viruses contained reassorted polymerase complexes with subunits derived from animal viruses, suggesting that the acquisition of a reassorted polymerase complex might...

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Bibliografische gegevens
Gepubliceerd in:J Gen Virol
Hoofdauteurs: Chin, Alex W. H., Yen, Hui-L., Krauss, Scott, Webby, Richard J., Poon, Leo L. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Microbiology Society 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804605/
https://ncbi.nlm.nih.gov/pubmed/26703222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000385
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