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Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex
The reassortment of influenza viral gene segments plays a key role in the genesis of pandemic strains. All of the last three pandemic viruses contained reassorted polymerase complexes with subunits derived from animal viruses, suggesting that the acquisition of a reassorted polymerase complex might...
Bewaard in:
Gepubliceerd in: | J Gen Virol |
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Hoofdauteurs: | , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Microbiology Society
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804605/ https://ncbi.nlm.nih.gov/pubmed/26703222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000385 |
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