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Novel point mutations in the ERG11 gene in clinical isolates of azole resistant Candida species

The azoles are the class of medications most commonly used to fight infections caused by Candida sp. Typically, resistance can be attributed to mutations in ERG11 gene (CYP51) which encodes the cytochrome P450 14α-demethylase, the primary target for the activity of azoles. The objective of this stud...

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Bibliographische Detailangaben
Veröffentlicht in:Mem Inst Oswaldo Cruz
Hauptverfasser: Silva, Danielly Beraldo dos Santos, Rodrigues, Luana Mireli Carbonera, de Almeida, Adriana Araújo, de Oliveira, Kelly Mari Pires, Grisolia/, Alexéia Barufatti
Format: Artigo
Sprache:Inglês
Veröffentlicht: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804502/
https://ncbi.nlm.nih.gov/pubmed/26982177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760150400
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