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TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene

Tumor suppressor p53 transcriptionally regulates hundreds of genes involved in various cellular functions. However, the detailed mechanisms underlying the selection of p53 targets in response to different stresses are still elusive. Here, we identify TFIIS.h, a transcription elongation factor, as a...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Liao, Jun-Ming, Cao, Bo, Deng, Jun, Zhou, Xiang, Strong, Michael, Zeng, Shelya, Xiong, Jianping, Flemington, Erik, Lu, Hua
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804275/
https://ncbi.nlm.nih.gov/pubmed/27005522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23542
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