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Clinical development of reovirus for cancer therapy: An oncolytic virus with immune-mediated antitumor activity
Reovirus is a double-stranded RNA virus with demonstrated oncolysis or preferential replication in cancer cells. The oncolytic properties of reovirus appear to be dependent, in part, on activated Ras signaling. In addition, Ras-transformation promotes reovirus oncolysis by affecting several steps of...
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| Publicado no: | World J Methodol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804250/ https://ncbi.nlm.nih.gov/pubmed/27019795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5662/wjm.v6.i1.25 |
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