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Activated Ras Signaling Pathways and Reovirus Oncolysis: An Update on the Mechanism of Preferential Reovirus Replication in Cancer Cells

The development of wild-type, unmodified Type 3 Dearing strain reovirus as an anticancer agent has currently expanded to 32 clinical trials (both completed and ongoing) involving reovirus in the treatment of cancer. It has been more than 30 years since the potential of reovirus as an anticancer agen...

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Detalhes bibliográficos
Main Authors: Gong, Jun, Mita, Monica M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071564/
https://ncbi.nlm.nih.gov/pubmed/25019061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00167
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