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Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation

Although proteins mediate highly ordered DNA organization in vivo, theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another even in the absence of proteins. Here we combine molecular dynamics simulations with single-molecule fluorescence resonance energy...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Yoo, Jejoong, Kim, Hajin, Aksimentiev, Aleksei, Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804163/
https://ncbi.nlm.nih.gov/pubmed/27001929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11045
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