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Direct evidence for sequence-dependent attraction between double-stranded DNA controlled by methylation

Although proteins mediate highly ordered DNA organization in vivo, theoretical studies suggest that homologous DNA duplexes can preferentially associate with one another even in the absence of proteins. Here we combine molecular dynamics simulations with single-molecule fluorescence resonance energy...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yoo, Jejoong, Kim, Hajin, Aksimentiev, Aleksei, Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804163/
https://ncbi.nlm.nih.gov/pubmed/27001929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11045
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