Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility

Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates mammalian fertility. Herein we demonstrate a critical role for the homeodomain transcription factor ventral anterior homeobox 1 (VAX1) in GnRH neuron maturation and sh...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Hoffmann, Hanne M., Trang, Crystal, Gong, Ping, Kimura, Ikuo, Pandolfi, Erica C., Mellon, Pamela L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804008/
https://ncbi.nlm.nih.gov/pubmed/27013679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2723-15.2016
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky