Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:l-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136(T)

The enzymes involved in synthesizing the bacterial cell wall are attractive targets for the design of antibacterial compounds, since this pathway is essential for bacteria and is absent in animals, particularly humans. A survey of the genome of a bacterium that belongs to the phylum Verrucomicrobia,...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Naqvi, Kubra F., Patin, Delphine, Wheatley, Matthew S., Savka, Michael A., Dobson, Renwick C. J., Gan, Han Ming, Barreteau, Hélène, Blanot, Didier, Mengin-Lecreulx, Dominique, Hudson, André O.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803751/
https://ncbi.nlm.nih.gov/pubmed/27047475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00362
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