Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:l-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136(T)

The enzymes involved in synthesizing the bacterial cell wall are attractive targets for the design of antibacterial compounds, since this pathway is essential for bacteria and is absent in animals, particularly humans. A survey of the genome of a bacterium that belongs to the phylum Verrucomicrobia,...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Naqvi, Kubra F., Patin, Delphine, Wheatley, Matthew S., Savka, Michael A., Dobson, Renwick C. J., Gan, Han Ming, Barreteau, Hélène, Blanot, Didier, Mengin-Lecreulx, Dominique, Hudson, André O.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803751/
https://ncbi.nlm.nih.gov/pubmed/27047475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00362
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