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Race-specific influence of CYP4F2 on dose and risk of hemorrhage among warfarin users

OBJECTIVE: The p.V433M in cytochrome P450 4F2 (rs2108622, CYP4F2*3) is associated with higher warfarin dose and lower risk of hemorrhage among European Americans. Herein, we evaluate the influence of CYP4F2*3 on warfarin dose, time to target INR and stable dose, proportion of time spent in target ra...

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Publicado en:Pharmacotherapy
Autores principales: Shendre, Aditi, Brown, Todd M., Liu, Nianjun, Hill, Charles E, Beasley, T. Mark, Nickerson, Deborah. A., Limdi, Nita. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803610/
https://ncbi.nlm.nih.gov/pubmed/26877068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1717
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