Race influences warfarin dose changes associated with genetic factors

Warfarin dosing algorithms adjust for race, assigning a fixed effect size to each predictor, thereby attenuating the differential effect by race. Attenuation likely occurs in both race groups but may be more pronounced in the less-represented race group. Therefore, we evaluated whether the effect of...

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Udgivet i:Blood
Main Authors: Limdi, Nita A., Brown, Todd M., Yan, Qi, Thigpen, Jonathan L., Shendre, Aditi, Liu, Nianjun, Hill, Charles E., Arnett, Donna K., Beasley, T. Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513254/
https://ncbi.nlm.nih.gov/pubmed/26024874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-627042
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