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Identification of DPY19L3 as the C-mannosyltransferase of R-spondin1 in human cells

R-spondin1 (Rspo1) is a secreted protein that enhances Wnt signaling, which has crucial functions in embryonic development and several cancers. C-mannosylation is a rare type of glycosylation and might regulate secretion, protein–protein interactions, and enzymatic activity. Although human Rspo1 con...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Niwa, Yuki, Suzuki, Takehiro, Dohmae, Naoshi, Simizu, Siro
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803301/
https://ncbi.nlm.nih.gov/pubmed/26764097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0373
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