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N-glycosylation is required for secretion and enzymatic activity of human hyaluronidase1
Hyaluronidase1 (HYAL1) is a hydrolytic enzyme that degrades hyaluronic acid (HA) and has three predicted N-glycosylation sites at Asn(99), Asn(216), and Asn(350). In this report, we show the functional significance of N-glycosylation on HYAL1 functions. Using mass spectrometry, we demonstrated that...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4087149/ https://ncbi.nlm.nih.gov/pubmed/25009769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.06.001 |
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