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Early Impairment of Lung Mechanics in a Murine Model of Marfan Syndrome

Early morbidity and mortality in patients with Marfan syndrome (MFS) -a connective tissue disease caused by mutations in fibrillin-1 gene- are mainly caused by aorta aneurysm and rupture. However, the increase in the life expectancy of MFS patients recently achieved by reparatory surgery promotes cl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Uriarte, Juan J., Meirelles, Thayna, Gorbenko del Blanco, Darya, Nonaka, Paula N., Campillo, Noelia, Sarri, Elisabet, Navajas, Daniel, Egea, Gustavo, Farré, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803219/
https://ncbi.nlm.nih.gov/pubmed/27003297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152124
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