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Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications

The “amyloid β hypothesis” of Alzheimer’s disease (AD) has been the reigning hypothesis explaining pathogenic mechanisms of AD over the last two decades. However, this hypothesis has not been fully validated in animal models, and several major unresolved issues remain. We recently developed a human...

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Detalhes bibliográficos
Publicado no:US Neurol
Main Authors: Choi, Se Hoon, Kim, Young Hye, D’Avanzo, Carla, Aronson, Jenna, Tanzi, Rudolph E., Kim, Doo Yeon
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803079/
https://ncbi.nlm.nih.gov/pubmed/27019672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17925/USN.2015.11.02.102
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