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Building up the nucleus: nuclear organization in the establishment of totipotency and pluripotency during mammalian development

In mammals, epigenetic reprogramming, the acquisition and loss of totipotency, and the first cell fate decision all occur within a 3-d window after fertilization from the one-cell zygote to the formation of the blastocyst. These processes are poorly understood in molecular detail, yet this is an ess...

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Publicat a:Genes Dev
Autors principals: Borsos, Máté, Torres-Padilla, Maria-Elena
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803048/
https://ncbi.nlm.nih.gov/pubmed/26980186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.273805.115
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