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Higher chromatin mobility supports totipotency and precedes pluripotency in vivo

The fusion of the gametes upon fertilization results in the formation of a totipotent cell. Embryonic chromatin is expected to be able to support a large degree of plasticity. However, whether this plasticity relies on a particular conformation of the embryonic chromatin is unknown. Moreover, whethe...

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Autores principales: Bošković, Ana, Eid, André, Pontabry, Julien, Ishiuchi, Takashi, Spiegelhalter, Coralie, Raghu Ram, Edupuganti V.S., Meshorer, Eran, Torres-Padilla, Maria-Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035533/
https://ncbi.nlm.nih.gov/pubmed/24831699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.238881.114
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