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Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening. We hypothesized that supplementation with tetrahydrobiopterin (BH (4)) would recouple endothelia...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Mäki‐Petäjä, Kaisa M., Day, Lisa, Cheriyan, Joseph, Hall, Frances C., Östör, Andrew J. K., Shenker, Nicholas, Wilkinson, Ian B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802470/
https://ncbi.nlm.nih.gov/pubmed/26896473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002762
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