Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis is a systemic inflammatory condition associated with increased cardiovascular risk that may be due to underlying endothelial dysfunction and subsequent aortic stiffening. We hypothesized that supplementation with tetrahydrobiopterin (BH (4)) would recouple endothelia...

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發表在:J Am Heart Assoc
Main Authors: Mäki‐Petäjä, Kaisa M., Day, Lisa, Cheriyan, Joseph, Hall, Frances C., Östör, Andrew J. K., Shenker, Nicholas, Wilkinson, Ian B.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802470/
https://ncbi.nlm.nih.gov/pubmed/26896473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002762
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