miR-34 activity is modulated through 5′-end phosphorylation in response to DNA damage

MicroRNA (miRNA) expression is tightly regulated by several mechanisms, including transcription and cleavage of the miRNA precursor RNAs, to generate a mature miRNA, which is thought to be directly correlated with activity. MiR-34 is a tumour-suppressor miRNA important in cell survival, that is tran...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Salzman, David W., Nakamura, Kotoka, Nallur, Sunitha, Dookwah, Michelle T., Metheetrairut, Chanatip, Slack, Frank J., Weidhaas, Joanne B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802117/
https://ncbi.nlm.nih.gov/pubmed/26996824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10954
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