A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer

Numerical centrosome aberrations underlie certain developmental abnormalities and may promote cancer. A cell maintains normal centrosome numbers by coupling centrosome duplication with segregation, which is achieved through sustained association of each centrosome with a mitotic spindle pole. Althou...

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Vydáno v:Nat Commun
Hlavní autoři: Chavali, Pavithra L., Chandrasekaran, Gayathri, Barr, Alexis R., Tátrai, Péter, Taylor, Chris, Papachristou, Evaggelia K., Woods, C. Geoffrey, Chavali, Sreenivas, Gergely, Fanni
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802056/
https://ncbi.nlm.nih.gov/pubmed/26987684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11005
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