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TOGp, the Human Homolog of XMAP215/Dis1, Is Required for Centrosome Integrity, Spindle Pole Organization, and Bipolar Spindle Assembly
The XMAP215/Dis1 MAP family is thought to regulate microtubule plus-end assembly in part by antagonizing the catastrophe-promoting function of kin I kinesins, yet XMAP215/Dis1 proteins localize to centrosomes. We probed the mitotic function of TOGp (human homolog of XMAP215/Dis1) using siRNA. Cells...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC379257/ https://ncbi.nlm.nih.gov/pubmed/14718566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0544 |
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