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Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency
Transcription factor Stat3 directs self‐renewal of pluripotent mouse embryonic stem (ES) cells downstream of the cytokine leukemia inhibitory factor (LIF). Stat3 upregulates pivotal transcription factors in the ES cell gene regulatory network to sustain naïve identity. Stat3 also contributes to the...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801951/ https://ncbi.nlm.nih.gov/pubmed/26903601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592629 |
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