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Defining an Essential Transcription Factor Program for Naïve Pluripotency
The gene regulatory circuitry through which pluripotent embryonic stem (ES) cells choose between self-renewal and differentiation appears vast and has yet to be distilled into an executive molecular program. Here we developed a data-constrained, computational approach to reduce complexity and derive...
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| Publicado no: | Science |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257066/ https://ncbi.nlm.nih.gov/pubmed/24904165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248882 |
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