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Emancipation from transcriptional latency: unphosphorylated STAT5 as guardian of hematopoietic differentiation

The canonical paradigm of Jak‐STAT signaling is that members of the signal transducers and activators of transcription (STATs) family of transcription factors are activated by Janus kinase (Jak)‐mediated tyrosine phosphorylation. While the relationship between activation and tyrosine phosphorylation...

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Detalhes bibliográficos
Publicado no:EMBO J
Autor principal: Decker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801946/
https://ncbi.nlm.nih.gov/pubmed/26893391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201693974
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