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Pseudouridines in U2 snRNA stimulate the ATPase activity of Prp5 during spliceosome assembly

Pseudouridine (Ψ) is the most abundant internal modification identified in RNA, and yet little is understood of its effects on downstream reactions. Yeast U2 snRNA contains three conserved Ψs (Ψ35, Ψ42, and Ψ44) in the branch site recognition region (BSRR), which base pairs with the pre‐mRNA branch...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wu, Guowei, Adachi, Hironori, Ge, Junhui, Stephenson, David, Query, Charles C, Yu, Yi‐Tao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801943/
https://ncbi.nlm.nih.gov/pubmed/26873591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593113
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