High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies

Stem cell therapies can promote neural repair and regeneration, yet controversy regarding optimal cell source and mechanism of action has slowed clinical translation, potentially due to undefined cellular heterogeneity. Single-cell resolution is needed to identify clinically relevant subpopulations...

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Bibliografski detalji
Izdano u:Front Neurol
Glavni autori: Rennert, Robert C., Schäfer, Richard, Bliss, Tonya, Januszyk, Michael, Sorkin, Michael, Achrol, Achal S., Rodrigues, Melanie, Maan, Zeshaan N., Kluba, Torsten, Steinberg, Gary K., Gurtner, Geoffrey C.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801858/
https://ncbi.nlm.nih.gov/pubmed/27047447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2016.00041
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