High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies

Stem cell therapies can promote neural repair and regeneration, yet controversy regarding optimal cell source and mechanism of action has slowed clinical translation, potentially due to undefined cellular heterogeneity. Single-cell resolution is needed to identify clinically relevant subpopulations...

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Vydáno v:Front Neurol
Hlavní autoři: Rennert, Robert C., Schäfer, Richard, Bliss, Tonya, Januszyk, Michael, Sorkin, Michael, Achrol, Achal S., Rodrigues, Melanie, Maan, Zeshaan N., Kluba, Torsten, Steinberg, Gary K., Gurtner, Geoffrey C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801858/
https://ncbi.nlm.nih.gov/pubmed/27047447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2016.00041
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