High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies

Stem cell therapies can promote neural repair and regeneration, yet controversy regarding optimal cell source and mechanism of action has slowed clinical translation, potentially due to undefined cellular heterogeneity. Single-cell resolution is needed to identify clinically relevant subpopulations...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Rennert, Robert C., Schäfer, Richard, Bliss, Tonya, Januszyk, Michael, Sorkin, Michael, Achrol, Achal S., Rodrigues, Melanie, Maan, Zeshaan N., Kluba, Torsten, Steinberg, Gary K., Gurtner, Geoffrey C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801858/
https://ncbi.nlm.nih.gov/pubmed/27047447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2016.00041
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