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MAF drives CD8(+) T-cell exhaustion
The molecular regulation of tumor induced T-cell exhaustion remains poorly characterized. Recently, we compared the transcriptome of “exhausted” CD8(+) T cells infiltrating melanomas to those of naive and acutely stimulated CD8(+) T cells. We demonstrated that MAF is over-expressed and plays a key r...
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| Publicado no: | Oncoimmunology |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801447/ https://ncbi.nlm.nih.gov/pubmed/27057466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1082707 |
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