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Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5’-Flanking Region

Oestrogens influence the pathology and development of hormone-sensitive breast cancers. Tissue factor pathway inhibitor (TFPI) has been shown to be associated with breast cancer pathogenesis. Recently, we found TFPI mRNA levels to be significantly reduced by oestrogens in a breast cancer cell line (...

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Pubblicato in:PLoS One
Autori principali: Ali, Huda Omar, Stavik, Benedicte, Myklebust, Christiane Filion, Andersen, Elisabeth, Dahm, Anders E. A., Iversen, Nina, Sandset, Per Morten, Skretting, Grethe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801176/
https://ncbi.nlm.nih.gov/pubmed/26999742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152114
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