Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5’-Flanking Region

Oestrogens influence the pathology and development of hormone-sensitive breast cancers. Tissue factor pathway inhibitor (TFPI) has been shown to be associated with breast cancer pathogenesis. Recently, we found TFPI mRNA levels to be significantly reduced by oestrogens in a breast cancer cell line (...

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Publicado no:PLoS One
Main Authors: Ali, Huda Omar, Stavik, Benedicte, Myklebust, Christiane Filion, Andersen, Elisabeth, Dahm, Anders E. A., Iversen, Nina, Sandset, Per Morten, Skretting, Grethe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801176/
https://ncbi.nlm.nih.gov/pubmed/26999742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152114
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