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Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease

Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown. We observed that treatment of healthy T cells with interleukin-12 induces upregulation of Fas ligand and Fas ligand...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Nabhani, Schafiq, Ginzel, Sebastian, Miskin, Hagit, Revel-Vilk, Shoshana, Harlev, Dan, Fleckenstein, Bernhard, Hönscheid, Andrea, Oommen, Prasad T., Kuhlen, Michaela, Thiele, Ralf, Laws, Hans-Jürgen, Borkhardt, Arndt, Stepensky, Polina, Fischer, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800681/
https://ncbi.nlm.nih.gov/pubmed/26113417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.114967
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