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Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease
Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20–30% of patients the genetic defect is unknown. We observed that treatment of healthy T cells with interleukin-12 induces upregulation of Fas ligand and Fas ligand...
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| Publicado no: | Haematologica |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4800681/ https://ncbi.nlm.nih.gov/pubmed/26113417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.114967 |
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