A Statistical Approach for Testing Cross-Phenotype Effects of Rare Variants

Increasing empirical evidence suggests that many genetic variants influence multiple distinct phenotypes. When cross-phenotype effects exist, multivariate association methods that consider pleiotropy are often more powerful than univariate methods that model each phenotype separately. Although sever...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Am J Hum Genet
Hlavní autoři: Broadaway, K. Alaine, Cutler, David J., Duncan, Richard, Moore, Jacob L., Ware, Erin B., Jhun, Min A., Bielak, Lawrence F., Zhao, Wei, Smith, Jennifer A., Peyser, Patricia A., Kardia, Sharon L.R., Ghosh, Debashis, Epstein, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800053/
https://ncbi.nlm.nih.gov/pubmed/26942286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.01.017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky